No spread to nearby lymph nodes or distant … Here are more details on each part of the TNM system for oral and oropharyngeal cancer. TNM Staging Of Oral Cancer 8,549 views. In 2016, the 8th edition of the American Joint Committee on Cancer (AJCC) TNM staging manual was released.1 As compared with the 7th edition, tumour infiltration depth and extranodal extension (ENE) were incorporated into the pathological TNM classification for oral squamous cell carcinoma (OSCC).1, 2 On the basis of the 8th edition criteria, 7th … CA: a cancer journal for clinicians. John Wiley & Sons: New York. T1 – The primary tumor is