Int J Cancer 121(11):2465–2472 CrossRef, Zurück zum Zitat Porceddu SV, Milne R, Brown E et al (2017) Validation of the ICON-S staging for HPV-associated oropharyngeal carcinoma using a pre-defined treatment policy. The 8th edition of the AJCC/UICC TNM-staging system for p16[HPV]-positive OPSCC manages to improve prediction of prognosis and will essentially influence choice of therapy in future. Oral Oncol 73:152–159 CrossRef, Zurück zum Zitat Coatesworth AP, MacLennan K (2002) Squamous cell carcinoma of the upper aerodigestive tract: the prevalence of microscopic extracapsular spread and soft tissue deposits in the clinically N0 neck. 16.10.2018 | Short Communication | Ausgabe 12/2018, Für Ihren Erfolg in Klinik und Praxis - Die beste Hilfe in Ihrem Arbeitsalltag als Mediziner. September 2020; European Archives of Oto-Rhino-Laryngology 277(2) DOI: … IMPORTANCE:The American Joint Committee on Cancer, 8th edition (AJCC-8) contains a new staging system for human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC). Hobelmann KC, Topf MC, Bar-Ad V, et al. Der Test läuft automatisch und formlos aus. The 8th edition AJCC/UICC TNM staging for p16-positive oropharyngeal carcinoma: is there space for i... Access to this full-text is provided by Springer Nature. BACKGROUND: The American Joint Committee on Cancer (AJCC) eighth edition introduces a staging system specific for human papilloma virus positive oropharyngeal cancer with separate clinical (AJCC 8c) and pathological (AJCC 8p) criteria. *. Figure 1. Introduction: The purpose of this study was to test whether the 8th edition of the AJCC/UICC TNM staging system (UICC) precisely... You are here. Aktuelle, verlässliche Information und Fortbildung für Ärzte im Berufsalltag. Locoregional and distant recurrence for HPV-associated oropharyngeal cancer using AJCC 8 staging In the largest evaluation of HPV + OPSCC after platinum-based chemoradiation using AJCC 8, risk for locoregional recurrence was stratified by smoking, T category, N category, and overall stage. This multicentre cohort study retrospectively examined the outcomes of 1907 non-metastatic (M0) HPV OPSCC patients treated in Europe and North America [ 8, 9 ]. Cancer 97(6):1464–1470 CrossRef, Zurück zum Zitat Lewis JS Jr, Carpenter DH, Thorstad WL, Zhang Q, Haughey BH (2011) Extracapsular extension is a poor predictor of disease recurrence in surgically treated oropharyngeal squamous cell carcinoma. Our study aim was to evaluate the effectiveness of the AJCC-8 relative to the AJCC 7th edition (AJCC-7). This list does not include typographical errors. Uniwersytet Medyczny im.Karola Marcinkowskiego w Poznaniu, Validation of the 8 edition UICC/AJCC TNM staging system for HPV associated oropharyngeal cancer patients managed with contemporary chemo-radiotherapy, Long-term analysis of transorally resected p16 + Oropharynx cancer: Outcomes and prognostic factors: Long-term Outcomes of p16 + Oropharynx Cancer, Predictors of Mortality in HPV‐Associated Oropharynx Carcinoma Treated With Surgery Alone, Impact of contralateral lymph nodal involvement and extranodal extension on survival of surgically managed HPV-positive oropharyngeal cancer staged with the AJCC eighth edition, Current status of human papillomavirus positivity in oropharyngeal squamous cell carcinoma in Europe: a systematic review, Radiologic Extranodal Extension Portends Worse Outcome in cN+ TNM8 Stage I Human Papillomavirus-Mediated Oropharyngeal Cancer, HPV as a marker for molecular characterization in head and neck oncology: Looking for a standardization of clinical use and of detection method(s) in clinical practice. This site contains important updates and errata identified in the first printing of the AJCC Cancer Staging Manual, 8 th Edition, and are effective for hard copy manuals purchased from September 2016 to February 2018. AJCC 8th edition staging has introduced a separate staging system for HPV mediated (p16+) squamous cell carcinomas of the oropharynx and HPV unrelated (p16-) squamous cell carcinoma of the oropharynx (AJCC: Cancer Staging [Accessed 20 September 2018], CAP: Protocol for the Examination of Specimens From Patients With Cancers of the Pharynx [Accessed 20 September 2018]) In response to these observations, the 8 th version of the AJCC staging system has been modified to account for the difference between HPV-related oropharyngeal tumors and other head and neck squamous cell carcinoma. The 8 th Ed has adopted the changes in T and N categories proposed by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S). 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